1H-Indazole, 5-bromo-7-(trifluoromethyl)-

1H-Indazole, 5-bromo-7-(trifluoromethyl)- - Names and Identifiers

Name	5-Bromo-7-(trifluoromethyl)-1H-indazole
Synonyms	5-broMo-7-(trifluoroMethyl)-1H-indazole 5-Bromo-7-(trifluoromethyl)-1H-indazole 1H-Indazole, 5-bromo-7-(trifluoromethyl)-
CAS	1374258-43-1
InChI	InChI=1S/C8H4BrF3N2/c9-5-1-4-3-13-14-7(4)6(2-5)8(10,11)12/h1-3H,(H,13,14)

1H-Indazole, 5-bromo-7-(trifluoromethyl)- - Physico-chemical Properties

Molecular Formula	C8H4BrF3N2
Molar Mass	265.03
Storage Condition	Sealed in dry,Room Temperature

1H-Indazole, 5-bromo-7-(trifluoromethyl)- - Introduction

5-Bromo-7-(trifluoromethyl)-lH-indazole is an organic compound with the chemical formula C8H4BrF3N.

Nature:
1. Appearance: colorless or light yellow crystal.
2. Melting point: about 55-58°C.
3. Boiling point: about 245°C.
4. Solubility: Slightly soluble in water, soluble in organic solvents such as methanol, ethanol, ether and dimethylformamide.

Use:
1.5-Bromo-7-(trifluoromethyl)-1H-indazole is a common synthetic intermediate, which can be used to prepare other organic compounds.
2. It has a wide range of applications in the field of medicine and can be used to research and develop new drugs.

Preparation Method:
There are many ways to prepare 5-bromo-7-(trifluoromethyl)-1H-indazole, and the following is one of the commonly used synthetic routes:
1. First, 2,4, 6-tribromopyridine is reacted with methyl trifluoroformate to obtain 2,4, 6-tribromo-5-(trifluoromethyl) pyridine.
2. Then, 2,4, 6-tribromo-5-(trifluoromethyl) pyridine is reacted with acetic acid, and 5-bromo-7-(trifluoromethyl)-1H-indazole is obtained through steps such as baking and hydrolysis.

Safety Information:
1.5-Bromo-7-(trifluoromethyl)-1H-indazole is an organic compound with certain chemical activity. Follow the safety procedures when using.
2. Inhalation, ingestion or exposure to the substance may cause irritation and damage to the human body. Use when wearing appropriate personal protective equipment, avoid direct contact with skin, eyes and mucous membranes.
3. storage should be sealed, away from the fire source and open flame.
4. In case of leakage, appropriate measures should be taken to clean up and dispose of the material to prevent the material from entering the environment and causing pollution.

Last Update：2024-04-09 21:01:54